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Related Articles詳細介紹
◆食品乳化 Food emulsification
◆制劑乳化 Preparation emulsification
◆化妝品乳化 Cosmetic emulsification
◆生物制劑 Biological preparations
微流控LNP,微流控包載,微流控mRNA原理介紹
Principle Introduction
可實現樣品的初乳化、復乳化、粒徑控制功能。
Can realize the functions of initial emulsification, re-emulsification and particle size control.
微流控乳化系統(tǒng)通過制備泵和高壓輸送泵與微流控芯片相連接，A相和B相可按照一定的比例恒速的輸送至芯片中進行混合，乳化。在微流控芯片中通過設計不同的流道結構，控制不同的速度，使得樣品在微流控芯片中達到湍流、層流或霧化狀態(tài)，可以實現樣品的初乳化或復乳化的要求。
Microfluidic emulsification system is connected with microfluidic chip by fabricating pump and high-pressure conveying pump. Phase A and phase B can be mixed and emulsified at constant speed in a certain proportion. In microfluidic chips, different runner structures are designed and different velocities are controlled to make the samples turbulent, laminar or atomized in the microfluidic chips, which can meet the requirements of pre-emulsification or re-emulsification.
制備好的樣品通過高壓泵輸送至高壓微流控芯片中，通過撞擊力和剪切力來控制粒徑，使其達到所需范圍內。粒徑小可達到100nm以內，PDI至0.1以下。
The prepared samples were transported to the high pressure microfluidic chip by high-pressure pump, and the particle size was controlled by impact force and shear force to reach the required range. The smallest particle size can be less than 100nm, and PDI can be less than 0.1.
技術參數
Technical Parameter
| 流量范圍（ml/min） Flow range | 0.1～200 | 流量連續(xù)可調 Continuously adjustable flow rate |
| 壓力范圍（MPa） Pressure | 0-25 | 具有高低壓保護功能 High and low voltage protection function |
| 溫度控制（℃） Temperature | ～100℃ | / |
| 流量設定誤差%（ml/min） Flow rate error | ≤±1% | / |
| 流量重復性誤差%（ml/min） Flow repeatability error | ≤1% | / |
| 壓力脈動（MPa） Pressure fluctuation | ≤0.1 | / |
| 壓力準確度（MPa） Pressure accuracy | ≤0.1 | / |
| 芯片通道尺寸 Chip channel size | 20um~1mm | 二通道，三通道，四通多或其他 Two-way, three-way, four-way or more |
微流控LNP,微流控脂質體,微流控包載,微流控mRNA
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